|Application ||WB, IHC-P, E|
|Calculated MW||104409 Da|
|Antigen Region||768-797 aa|
|Other Names||Multimerin-2, EMILIN-3, Elastin microfibril interface located protein 3, Elastin microfibril interfacer 3, EndoGlyx-1 p125/p140 subunit, MMRN2, EMILIN3|
|Target/Specificity||This MMRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 768-797 amino acids from the C-terminal region of human MMRN2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MMRN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
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Provided below are standard protocols that you may find useful for product applications.
Leimeister, C., et al. Dev. Biol. 249(2):204-218(2002)
Christian, S., et al. J. Biol. Chem. 276(51):48588-48595(2001)
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