- CITATIONS: 1
|Application ||WB, IHC-P, E|
|Calculated MW||36598 Da|
|Antigen Region||194-229 aa|
|Other Names||Apoptosis facilitator Bcl-2-like protein 14, Bcl2-L-14, Apoptosis regulator Bcl-G, BCL2L14, BCLG|
|Target/Specificity||This Bcl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-229 amino acids from human Bcl.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Bcl-G BH3 Domain Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in apoptosis.|
|Cellular Location||Cytoplasm. Isoform 2: Endomembrane system. Note=Predominantly localized to cytosolic organelles|
|Tissue Location||Isoform 1 is widely expressed. Isoform 2 is testis-specific.|
Provided below are standard protocols that you may find useful for product applications.
Bcl-G belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of Bcl-G has been shown to induce apoptosis in cells.
Ozalp, S.S., et al., Eur J Gynaecol Oncol 23(5):419-422 (2002).
Guo, B., et al., J. Biol. Chem. 276(4):2780-2785 (2001).
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