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ERLIN1 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP13078c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP13078c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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ERLIN1 Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | O75477 |
| Other Accession | Q91X78, NP_001094096.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 38926 Da |
ERLIN1 Antibody (Center) - Additional info | |
| Gene ID 10613 | |
| Other Names ERLIN1; C10orf69; KE04; KEO4; SPFH1; Erlin-1; Endoplasmic reticulum lipid raft-associated protein 1; Protein KE04; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1 | |
| Target/Specificity This ERLIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-275 amino acids from the Central region of human ERLIN1. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ERLIN1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ERLIN1 Antibody (Center) - Protein Information | |
| Name ERLIN1 | |
| Synonyms C10orf69, KE04, KEO4, SPFH1 | |
| Function Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) | |
| Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Associated with lipid raft-like domains of the endoplasmic reticulum membrane | |
| Tissue Location Expressed in heart, placenta, liver, kidney, pancreas, prostate, testis, ovary and small intestine | |
ERLIN1 Antibody (Center) - Related products
AP13078c: ERLIN1 Antibody (Center)
ERLIN1 Antibody (Center) - Application data
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ERLIN1 Antibody (Center) (Cat. #AP13078c) western blot analysis in HepG2,A549 cell line lysates (35ug/lane).This demonstrates the ERLIN1 antibody detected the ERLIN1 protein (arrow).
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ERLIN1 Antibody (Center) (Cat. #AP13078c)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ERLIN1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
ERLIN1 Antibody (Center) - Research Areas
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BACKGROUND
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs).
REFERENCES
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Martins-de-Souza, D., et al. J Psychiatr Res (2010) In press : Wang, Y., et al. Biochim. Biophys. Acta 1793(11):1710-1718(2009) Pearce, M.M., et al. J. Biol. Chem. 284(16):10433-10445(2009) Yuan, X., et al. Am. J. Hum. Genet. 83(4):520-528(2008)
