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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Bmf BH3 Domain Antibody   

Bmf BH3 Domain Antibody

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Bmf BH3 Domain Antibody AP1309a
    Western blot analysis of anti-Bmf BH3 Domain Antibody (Cat.#AP1309a) in A2058 cell line lysates (35ug/lane). Bmf(arrow) was detected using the purified Pab.
  • IHC-P - Bmf BH3 Domain Antibody AP1309a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96LC9
Other Accession Q91ZE9
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 20508 Da
Antigen Region 115-150 aa
Additional Information
Gene ID 90427
Other Names Bcl-2-modifying factor, BMF
Target/Specificity This Bmf BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-150 amino acids from human Bmf BH3 Domain.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBmf BH3 Domain Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BMF
Function May play a role in apoptosis. Isoform 1 seems to be the main initiator.
Tissue Location Isoform 1 is mainly expressed in B-lymphoid cells. Isoform 2 and isoform 3 are mainly expressed in B-CLL and normal B-cells.
Research Areas
Citations (0)

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Bmf belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis.


Puthalakath, H., et al., Science 293(5536):1829-1832 (2001).

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Cat# AP1309a
(40 western blots)
Availability: Inquire
Bulk Size
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