|Application ||WB, E|
|Other Accession||NP_001181921.1, NP_001181920.1, NP_001181919.1, NP_062552.2|
|Calculated MW||74355 Da|
|Antigen Region||239-267 aa|
|Other Names||7SK snRNA methylphosphate capping enzyme, MePCE, 211-, Bicoid-interacting protein 3 homolog, Bin3 homolog, MEPCE, BCDIN3|
|Target/Specificity||This MEPCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the Central region of human MEPCE.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MEPCE Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.|
|Tissue Location||Expressed in chronic myeloid leukemia cells, adrenal gland, brain, cerebellum, kidney, lung, mammary gland and testis. Weakly or not expressed in other tissues|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.
Xue, Y., et al. Nucleic Acids Res. 38(2):360-369(2010)
Krueger, B.J., et al. Nucleic Acids Res. 36(7):2219-2229(2008)
Kaneko, S., et al. Proc. Natl. Acad. Sci. U.S.A. 104(45):17620-17625(2007)
Jeronimo, C., et al. Mol. Cell 27(2):262-274(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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