|Application ||WB, E|
|Other Accession||NP_001181921.1, NP_001181920.1, NP_001181919.1, NP_062552.2|
|Calculated MW||74355 Da|
|Antigen Region||239-267 aa|
|Other Names||7SK snRNA methylphosphate capping enzyme, MePCE, 211-, Bicoid-interacting protein 3 homolog, Bin3 homolog, MEPCE, BCDIN3|
|Target/Specificity||This MEPCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the Central region of human MEPCE.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MEPCE Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.|
|Tissue Location||Expressed in chronic myeloid leukemia cells, adrenal gland, brain, cerebellum, kidney, lung, mammary gland and testis. Weakly or not expressed in other tissues|
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Provided below are standard protocols that you may find useful for product applications.
S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.
Xue, Y., et al. Nucleic Acids Res. 38(2):360-369(2010)
Krueger, B.J., et al. Nucleic Acids Res. 36(7):2219-2229(2008)
Kaneko, S., et al. Proc. Natl. Acad. Sci. U.S.A. 104(45):17620-17625(2007)
Jeronimo, C., et al. Mol. Cell 27(2):262-274(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.