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GGT7 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9UJ14 |
| Other Accession | Q99MZ4, Q99JP7, NP_821158.2 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 70467 Da |
| Antigen Region | 24-53 aa |
| Gene ID | 2686 |
|---|---|
| Other Names | Gamma-glutamyltransferase 7, GGT 7, Gamma-glutamyltransferase-like 3, Gamma-glutamyltransferase-like 5, Gamma-glutamyltranspeptidase 7, Glutathione hydrolase 7, Gamma-glutamyltransferase 7 heavy chain, Gamma-glutamyltransferase 7 light chain, GGT7, GGTL3, GGTL5 |
| Target/Specificity | This GGT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human GGT7. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GGT7 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GGT7 (HGNC:4259) |
|---|---|
| Synonyms | GGTL3, GGTL5 |
| Function | Hydrolyzes and transfers gamma-glutamyl moieties from glutathione and other gamma-glutamyl compounds to acceptors. |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:P19440}; Single- pass type II membrane protein {ECO:0000250|UniProtKB:P07314} |
| Tissue Location | Widely expressed, but at low level, except in the airway epithelial cells. Detected in brain, heart, kidney, liver, lung, spleen, testis and trachea |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Heisterkamp, N., et al. Hum. Genet. 123(4):321-332(2008)
He, X., et al. Biochem. Biophys. Res. Commun. 297(3):528-536(2002)
Figlewicz, D.A., et al. Genomics 17(2):299-305(1993)
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