|Application ||WB, IHC-P, E|
|Calculated MW||79144 Da|
|Antigen Region||290-318 aa|
|Other Names||Calpain-8, New calpain 2, nCL-2, Stomach-specific M-type calpain, CAPN8, NCL2|
|Target/Specificity||This CAPN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-318 amino acids from the Central region of human CAPN8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CAPN8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity).|
|Cellular Location||Cytoplasm. Golgi apparatus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex (By similarity).
Hata, S., et al. J. Biol. Chem. 282(38):27847-27856(2007)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Hata, S., et al. J. Mol. Evol. 53(3):191-203(2001)
Huang, Y., et al. Trends Mol Med 7(8):355-362(2001)
Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.