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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CX001 Antibody (C-term)   

CX001 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CX001 Antibody (C-term) AP13165b
    CX001 Antibody (C-term) (Cat. #AP13165b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CX001 antibody detected the CX001 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O96002
Other Accession NP_004700.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 62-90 aa
Additional Information
Other Names Transmembrane protein 257, TMEM257, CXorf1
Target/Specificity This CX001 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the C-terminal region of human CX001.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCX001 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMEM257
Synonyms CXorf1
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Brain. In the hippocampus it is mainly localized in the granular-cell layer of the dentate gyrus and in the CA2-CA3 subfields of Ammon's horn EMBL; Y10607; CAA71614.1; -; Genomic_DNA EMBL; Y08902; CAA70110.1; -; mRNA EMBL; AL109653; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC113600; AAI13601.1; -; mRNA EMBL; BC113604; AAI13605.1; -; mRNA CCDS; CCDS14681.1; - RefSeq; NP_004700.1; NM_004709.2 UniGene; Hs.106688; - ProteinModelPortal; O96002; - iPTMnet; O96002; - PhosphoSitePlus; O96002; - BioMuta; TMEM257; - PaxDb; O96002; - PRIDE; O96002; - DNASU; 9142; - Ensembl; ENST00000408967; ENSP00000386149; ENSG00000221870 GeneID; 9142; - KEGG; hsa:9142; - UCSC; uc004fch.4; human CTD; 9142; - GeneCards; TMEM257; - H-InvDB; HIX0056114; - HGNC; HGNC:2562; TMEM257 HPA; HPA028857; - MIM; 300565; gene neXtProt; NX_O96002; - OpenTargets; ENSG00000221870; - PharmGKB; PA27059; - eggNOG; ENOG410KCJN; Eukaryota eggNOG; ENOG4110NW9; LUCA GeneTree; ENSGT00510000055407; - HOGENOM; HOG000112096; - InParanoid; O96002; - OMA; TIFYFRI; - OrthoDB; EOG091G0WPJ; - PhylomeDB; O96002; - BioCyc; ZFISH:G66-31656-MONOMER; - GenomeRNAi; 9142; - PRO; PR:O96002; - Proteomes; UP000005640; Chromosome X Bgee; ENSG00000221870; - CleanEx; HS_CXorf1; - Genevisible; O96002; HS GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW 2: Evidence at transcript level; Complete proteome; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix CHAIN 1 111 Transmembrane protein 257 /FTId=PRO_0000079729 TRANSMEM 23 43 Helical. TRANSMEM 58 78 Helical. VARIANT 36 36 S -> A (in dbSNP:rs3752359) /FTId=VAR_033766 SEQUENCE 111 AA; 13452 MW; 5EFA883C1329A522 CRC64; MYSRLFYLKS SYIIYFEPLF SNAIINILSF INSLASPLTI FCFALSAQAL STIFYFRIFI FIFHSWILLF HFYFTCSFKT YEHQHSKMVP AYRMQSPRAL PRTYLYVWPY K
Research Areas
Citations (0)

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This intronless gene is expressed in the hippocampus and maps close to a candidate region for several X-linked mental retardation (XLMR) syndromes. It is conserved in primates, cow, and horse, but not found in mouse and rat. The exact function of this gene is not known, but on the basis of its physical location and expression pattern, it is proposed to have an important function in the brain.


Ross, M.T., et al. Nature 434(7031):325-337(2005)
Redolfi, E., et al. DNA Cell Biol. 17(12):1009-1016(1998)

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$ 295.00
$ 99.00
Cat# AP13165b
(40 western blots)
Availability: In Stock
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