|Application ||WB, IHC-P, FC, E|
|Other Accession||Q5E9E4, NP_003136.1|
|Calculated MW||20135 Da|
|Antigen Region||154-183 aa|
|Other Names||Translocon-associated protein subunit beta, TRAP-beta, Signal sequence receptor subunit beta, SSR-beta, SSR2, TRAPB|
|Target/Specificity||This SSR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the C-terminal region of human SSR2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SSR2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type I membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Sikorska, M., et al. J. Neurosci. Res. 86(8):1680-1693(2008)
Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003)
Wang, L., et al. FEBS Lett. 457(3):316-322(1999)
Dodson, G., et al. Curr. Opin. Struct. Biol. 8(2):189-194(1998)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.