|Application ||WB, E|
|Other Accession||Q9WU63, NP_055135.1|
|Calculated MW||22875 Da|
|Antigen Region||18-47 aa|
|Other Names||Heme-binding protein 2, Placental protein 23, PP23, Protein SOUL, HEBP2, C6orf34, SOUL|
|Target/Specificity||This HEBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-47 amino acids from the N-terminal region of human HEBP2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HEBP2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions. Does not bind hemin.|
|Cellular Location||Cytoplasm. Mitochondrion. Note=Mainly localized to the cytoplasm with a much lower abundance in the mitochondrion|
|Tissue Location||Detected in placenta.|
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Provided below are standard protocols that you may find useful for product applications.
HEBP2 can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions.
Szigeti, A., et al. J. Biol. Chem. 285(3):2140-2151(2010)
Freire, F., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65 (PT 7), 723-726 (2009) :
Szigeti, A., et al. FEBS Lett. 580(27):6447-6454(2006)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Liu, L., et al. Genomics 79(1):124-136(2002)
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