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ABCC12 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP13196c 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP13196c-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
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ABCC12 Antibody (Center) - Product info

ApplicationWB, IHC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ96J65
Other AccessionNP_150229.2
ReactivityMouse
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW152297 Da

ABCC12 Antibody (Center) - Additional info

Gene ID 94160
Other Names
ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12
Target/Specificity
This ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 722-751 amino acids from the Central region of human ABCC12.
Dilution
WB~~1:100~500
IHC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
ABCC12 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.

ABCC12 Antibody (Center) - Protein Information

Name ABCC12
Synonyms MRP9
Function
Probable transporter (By similarity).
Cellular Location
Membrane; Multi-pass membrane protein (Potential)
Tissue Location
Expressed in testis (at protein level). Widely expressed at low level. Isoform 5 is specifically expressed in brain, testis and breast cancer cells

ABCC12 Antibody (Center) - Related products

AP13196c: ABCC12 Antibody (Center)

ABCC12 Antibody (Center) - Application data

  • ABCC12 Antibody (Center) (Cat. #AP13196c) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the ABCC12 antibody detected the ABCC12 protein (arrow).

  • ABCC12 Antibody (Center) (Cat. #AP13196c)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABCC12 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

ABCC12 Antibody (Center) - Research Areas

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BACKGROUND

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.

REFERENCES

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Haimeur, A., et al. Curr. Drug Metab. 5(1):21-53(2004) Bera, T.K., et al. Proc. Natl. Acad. Sci. U.S.A. 99(10):6997-7002(2002) Yabuuchi, H., et al. Biochem. Biophys. Res. Commun. 288(4):933-939(2001) Tammur, J., et al. Gene 273(1):89-96(2001)