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AFG3L2 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
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| Catalog # | Size | Availability | Price | |
| AP13219a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP13219a-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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AFG3L2 Antibody (N-term) - Product info | |
| Application | WB, IHC
|
| Primary Accession | Q9Y4W6 |
| Other Accession | Q8JZQ2, Q2KJI7, NP_006787.2 |
| Reactivity | Human |
| Predicted | Bovine, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 88584 Da |
AFG3L2 Antibody (N-term) - Additional info | |
| Gene ID 10939 | |
| Other Names AFG3L2; AFG3-like protein 2; Paraplegin-like protein | |
| Target/Specificity This AFG3L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 amino acids from the N-terminal region of human AFG3L2. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AFG3L2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
AFG3L2 Antibody (N-term) - Protein Information | |
| Name AFG3L2 | |
| Function ATP-dependent protease which is essential for axonal development (By similarity) | |
| Cellular Location Mitochondrion membrane; Multi-pass membrane protein | |
| Tissue Location Ubiquitous. Highly expressed in the cerebellar Purkinje cells | |
AFG3L2 Antibody (N-term) - Related products
AFG3L2 Antibody (N-term) - Application data
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AFG3L2 Antibody (N-term) (Cat. #AP13219a) western blot analysis in MDA-MB453,MCF-7,Jurkat cell line lysates (35ug/lane).This demonstrates the AFG3L2 antibody detected the AFG3L2 protein (arrow).
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AFG3L2 Antibody (N-term) (Cat. #AP13219a)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AFG3L2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
AFG3L2 Antibody (N-term) - Research Areas
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BACKGROUND
This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
REFERENCES
Edener, U., et al. Eur. J. Hum. Genet. 18(8):965-968(2010) Di Bella, D., et al. Nat. Genet. 42(4):313-321(2010) Augustin, S., et al. Mol. Cell 35(5):574-585(2009) Mariotti, C., et al. Cerebellum 7(2):184-188(2008) Cagnoli, C., et al. Brain 129 (PT 1), 235-242 (2006) :
