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GFRA4 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GFRA4 Antibody (Center) AP13249c
    GFRA4 Antibody (Center) (Cat. #AP13249c) western blot analysis in HL-60,ZR-75-1,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the GFRA4 antibody detected the GFRA4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9GZZ7
Other Accession NP_665705.1, NP_071422.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 31670 Da
Antigen Region 156-184 aa
Additional Information
Gene ID 64096
Other Names GDNF family receptor alpha-4, GDNF receptor alpha-4, GDNFR-alpha-4, GFR-alpha-4, Persephin receptor, GFRA4
Target/Specificity This GFRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human GFRA4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGFRA4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GFRA4
Function Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
Cellular Location Isoform GFRalpha4a: Cell membrane; Lipid- anchor, GPI-anchor Isoform GFRalpha4c: Secreted.
Tissue Location Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.


Yang, J., et al. FEBS Lett. 569 (1-3), 267-271 (2004) :
Borrego, S., et al. J. Med. Genet. 40 (3), E18 (2003) :
Deloukas, P., et al. Nature 414(6866):865-871(2001)
Zhou, B., et al. Pediatr. Neurol. 25(2):156-161(2001)
Lindahl, M., et al. J. Biol. Chem. 276(12):9344-9351(2001)

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$ 295.00
$ 99.00
Cat# AP13249c
(40 western blots)
Availability: In Stock
Bulk Size
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