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PNPLA1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PNPLA1 Antibody (N-term) AP13348A
    PNPLA1 Antibody (N-term) (Cat. #AP13348a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PNPLA1 antibody detected the PNPLA1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8N8W4
Other Accession NP_001139188.1, NP_001139189.2, NP_775947.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 57875 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 285848
Other Names Patatin-like phospholipase domain-containing protein 1, 311-, PNPLA1
Target/Specificity This PNPLA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PNPLA1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPNPLA1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Lipid hydrolase. Important in the formation of the epidermal lipid barrier. Plays a role in glycerophospholipid metabolism.
Cellular Location Cytoplasm. Note=Clearly distributed in the cytoplasm of keratinocytes
Tissue Location Expressed in the digestive system. Expressed in the epidermis of skin keratinocytes. Strongly expressed in the granular layer. Expressed in the upper epidermis and eccrine sweat glands of the dermis and in the region of keratin filament bundles, which is more pronounced in upper epidermal layers and in the lower cornified layers.
Research Areas
Citations (0)

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Human patatin-like phospholipases, such as PNPLA1, have been implicated in regulation of adipocyte differentiation and have been induced by metabolic stimuli (Wilson et al., 2006 [PubMed 16799181]).


Kienesberger, P.C., et al. J. Lipid Res. 50 SUPPL, S63-S68 (2009) :
Johansson, L.E., et al. PLoS ONE 4 (4), E5327 (2009) :
De Chaudhuri, S., et al. Environ. Health Perspect. 116(4):501-505(2008)
Wilson, P.A., et al. J. Lipid Res. 47(9):1940-1949(2006)

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$ 295.00
$ 99.00
Cat# AP13348A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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