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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RAB21 Antibody (C-term)   

RAB21 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RAB21 Antibody (C-term) AP13377b
    RAB21 Antibody (C-term) (Cat. #AP13377b) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the RAB21 antibody detected the RAB21 protein (arrow).
  • IHC-P - RAB21 Antibody (C-term) AP13377b
    RAB21 Antibody (C-term) (Cat. #AP13377b)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RAB21 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UL25
Other Accession Q6AXT5, P35282, Q17R06, NP_055814.1
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 24348 Da
Antigen Region 168-197 aa
Additional Information
Gene ID 23011
Other Names Ras-related protein Rab-21, RAB21, KIAA0118
Target/Specificity This RAB21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human RAB21.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRAB21 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB21
Synonyms KIAA0118
Function Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity).
Cellular Location Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus, trans- Golgi network. Golgi apparatus membrane. Early endosome membrane. Cytoplasmic vesicle membrane Cleavage furrow. Note=Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm. During mitosis, in mid- telophase, localized in the ingressing cleavage furrow. In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells. {ECO:0000250|UniProtKB:P35282, ECO:0000250|UniProtKB:Q6AXT5}
Tissue Location Widely expressed. In jejunal tissue, predominantly expressed in the apical region of the epithelial cell layer of the villi, weak expression, if any, in the crypt epithelium. Capillary endothelium and some cell types in the lamina propria also show expression
Research Areas
Citations (0)

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RAB21 belongs to the RAB family of small GTP-binding proteins that regulate intracellular vesicle targeting (Opdam et al., 2000 [PubMed 10887961]).


Burgo, A., et al. EMBO Rep. 10(10):1117-1124(2009)
Pellinen, T., et al. Dev. Cell 15(3):371-385(2008)
Delprato, A., et al. Nat. Struct. Mol. Biol. 14(5):406-412(2007)
Pellinen, T., et al. J. Cell Biol. 173(5):767-780(2006)
Eathiraj, S., et al. Nature 436(7049):415-419(2005)

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$ 295.00
$ 99.00
Cat# AP13377b
(40 western blots)
Availability: In Stock
Bulk Size
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