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KCTD10 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q9H3F6 |
| Other Accession | NP_114160.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35432 Da |
| Antigen Region | 273-301 aa |
| Gene ID | 83892 |
|---|---|
| Other Names | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3, hBACURD3, BTB/POZ domain-containing protein KCTD10, Potassium channel tetramerization domain-containing protein 10, KCTD10, ULR061 |
| Target/Specificity | This KCTD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the C-terminal region of human KCTD10. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KCTD10 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KCTD10 |
|---|---|
| Synonyms | ULR061 |
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity).
References
Keebler, M.E., et al. Circ Cardiovasc Genet 3(4):358-364(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Junyent, M., et al. Am. J. Clin. Nutr. 90(3):686-694(2009)
Wang, Y., et al. J. Cell. Biochem. 106(3):409-413(2009)
Liu, R., et al. FEBS J. 276(4):1114-1124(2009)
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