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TBCC Antibody (N-term )

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TBCC Antibody (N-term ) AP13475a
    TBCC Antibody (N-term ) (Cat. #AP13475a) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the TBCC antibody detected the TBCC protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15814
Other Accession NP_003183.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39248 Da
Antigen Region 20-49 aa
Additional Information
Gene ID 6903
Other Names Tubulin-specific chaperone C, Tubulin-folding cofactor C, CFC, TBCC
Target/Specificity This TBCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human TBCC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTBCC Antibody (N-term ) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
Cellular Location Cytoplasm. Note=Detected predominantly in the photoreceptor connecting cilium
Tissue Location Expressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecting cilium at the tips of the IS (at protein level).
Research Areas
Citations (0)

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Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.


Hage-Sleiman, R., et al. BMC Cancer 10, 135 (2010) :
Nature 447(7145):661-678(2007)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Bartolini, F., et al. J. Biol. Chem. 277(17):14629-14634(2002)
Tian, G., et al. Cell 86(2):287-296(1996)

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$ 295.00
$ 99.00
Cat# AP13475a
(40 western blots)
Availability: In Stock
Bulk Size
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