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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   DTX3 Antibody (N-term )   

DTX3 Antibody (N-term )

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DTX3 Antibody (N-term ) AP13476a
    DTX3 Antibody (N-term ) (Cat. #AP13476a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the DTX3 antibody detected the DTX3 protein (arrow).
  • WB - DTX3 Antibody (N-term ) AP13476a
    DTX3 Antibody (N-term ) (Cat. #AP13476a) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the DTX3 antibody detected the DTX3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8N9I9
Other Accession Q80V91, NP_848597.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37988 Da
Antigen Region 20-48 aa
Additional Information
Gene ID 196403
Other Names Probable E3 ubiquitin-protein ligase DTX3, 632-, Protein deltex-3, Deltex3, RING finger protein 154, DTX3, RNF154
Target/Specificity This DTX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from the N-terminal region of human DTX3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDTX3 Antibody (N-term ) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DTX3
Synonyms RNF154
Function Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).


Chastagner, P., et al. EMBO Rep. 7(11):1147-1153(2006)
Takeyama, K., et al. J. Biol. Chem. 278(24):21930-21937(2003)
Kishi, N., et al. Int. J. Dev. Neurosci. 19(1):21-35(2001)
Matsuno, K., et al. Development 121(8):2633-2644(1995)

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Cat# AP13476a
(40 western blots)
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