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PROC Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PROC Antibody (Center) AP13543c
    All lanes : Anti-PROC Antibody (Center) at 1:500-1:1000 dilution Lane 1: human liver lysate Lane 2: human plasma lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IF - PROC Antibody (Center) AP13543c
    Confocal immunofluorescent analysis of PROC Antibody (Center) (Cat#AP13543c) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
  • IHC-P - PROC Antibody (Center) AP13543c
    PROC Antibody (Center) (Cat. #AP13543c)immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PROC Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04070
Other Accession NP_000303.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 52071 Da
Antigen Region 177-206 aa
Additional Information
Gene ID 5624
Other Names Vitamin K-dependent protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, Vitamin K-dependent protein C light chain, Vitamin K-dependent protein C heavy chain, Activation peptide, PROC
Target/Specificity This PROC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human PROC.
Dilution WB~~1:500-1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPROC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.
Cellular Location Secreted.
Tissue Location Plasma; synthesized in the liver.
Research Areas
Citations (0)

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This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.


Tang, W., et al. Blood (2010) In press :
Agapkina, Iu.V., et al. Mol. Biol. (Mosk.) 44(4):613-619(2010)
Witt, I., et al. Blood Coagul. Fibrinolysis 5(4):651-653(1994)
Zhang, L., et al. Blood 80(4):942-952(1992)
Grundy, C.B., et al. Hum. Genet. 89(6):683-684(1992)

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$ 295.00
$ 99.00
Cat# AP13543c
(40 western blots)
Availability: In Stock
Bulk Size
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