|Application ||WB, E|
|Other Accession||Q9WTY1, NP_005698.1|
|Antigen Region||390-419 aa|
|Other Names||Programmed cell death protein 7, ES18, hES18, PDCD7|
|Target/Specificity||This PDCD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-419 amino acids from the C-terminal region of human PDCD7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PDCD7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes apoptosis when overexpressed.|
|Cellular Location||Nucleus. EMBL; AK096970; BAC04915.1; -; mRNA EMBL; AF083930; AAD20241.1; -; mRNA EMBL; BC016992; AAH16992.2; -; mRNA EMBL; BT007395; AAP36059.1; -; mRNA CCDS; CCDS10201.1; - RefSeq; NP_005698.1; NM_005707.1 UniGene; Hs.458596; - ProteinModelPortal; Q8N8D1; - SMR; Q8N8D1; - BioGrid; 115390; 29 CORUM; Q8N8D1; - IntAct; Q8N8D1; 10 MINT; Q8N8D1; - STRING; 9606.ENSP00000204549; - iPTMnet; Q8N8D1; - PhosphoSitePlus; Q8N8D1; - BioMuta; PDCD7; - DMDM; 38258174; - EPD; Q8N8D1; - MaxQB; Q8N8D1; - PaxDb; Q8N8D1; - PeptideAtlas; Q8N8D1; - PRIDE; Q8N8D1; - ProteomicsDB; 72402; - DNASU; 10081; - Ensembl; ENST00000204549; ENSP00000204549; ENSG00000090470 GeneID; 10081; - KEGG; hsa:10081; - UCSC; uc002aol.3; human CTD; 10081; - DisGeNET; 10081; - EuPathDB; HostDB:ENSG00000090470.14; - GeneCards; PDCD7; - HGNC; HGNC:8767; PDCD7 HPA; HPA049388; - MIM; 608138; gene neXtProt; NX_Q8N8D1; - OpenTargets; ENSG00000090470; - PharmGKB; PA33117; - eggNOG; ENOG410IVC0; Eukaryota eggNOG; ENOG41124DX; LUCA GeneTree; ENSGT00390000017392; - HOGENOM; HOG000115476; - HOVERGEN; HBG053537; - InParanoid; Q8N8D1; - OMA; WDSFIRA; - OrthoDB; EOG091G0R7S; - PhylomeDB; Q8N8D1; - TreeFam; TF332996; - Reactome; R-HSA-72165; mRNA Splicing - Minor Pathway ChiTaRS; PDCD7; human GeneWiki; PDCD7; - GenomeRNAi; 10081; - PRO; PR:Q8N8D1; - Proteomes; UP000005640; Chromosome 15 Bgee; ENSG00000090470; - CleanEx; HS_PDCD7; - ExpressionAtlas; Q8N8D1; baseline and differential Genevisible; Q8N8D1; HS GO; GO:0005654; C:nucleoplasm; TAS:Reactome GO; GO:0005689; C:U12-type spliceosomal complex; IDA:HGNC GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome GO; GO:0051384; P:response to glucocorticoid; ISS:HGNC GO; GO:0008380; P:RNA splicing; IC:HGNC InterPro; IPR031974; PDCD7 Pfam; PF16021; PDCD7; 1 1: Evidence at protein level; Apoptosis; Coiled coil; Complete proteome; Nucleus; Reference proteome; Repeat CHAIN 1 485 Programmed cell death protein 7 /FTId=PRO_0000058269 COILED 232 335 COILED 362 411 COMPBIAS 4 129 Pro-rich COMPBIAS 236 278 Arg/Glu-rich CONFLICT 292 292 Q -> GE (in Ref. 2; AAD20241) CONFLICT 303 303 S -> A (in Ref. 2; AAD20241) SEQUENCE 485 AA; 54700 MW; FF907D6D2187832A CRC64; MALPPFFGQG RPGPPPPQPP PPAPFGCPPP PLPSPAFPPP LPQRPGPFPG ASAPFLQPPL ALQPRASAEA SRGGGGAGAF YPVPPPPLPP PPPQCRPFPG TDAGERPRPP PPGPGPPWSP RWPEAPPPPA DVLGDAALQR LRDRQWLEAV FGTPRRAGCP VPQRTHAGPS LGEVRARLLR ALRLVRRLRG LSQALREAEA DGAAWVLLYS QTAPLRAELA ERLQPLTQAA YVGEARRRLE RVRRRRLRLR ERAREREAER EAEAARAVER EQEIDRWRVK CVQEVEEKKR EQELKAAADG VLSEVRKKQA DTKRMVDILR ALEKLRKLRK EAAARKGVCP PASADETFTH HLQRLRKLIK KRSELYEAEE RALRVMLEGE QEEERKRELE KKQRKEKEKI LLQKREIESK LFGDPDEFPL AHLLEPFRQY YLQAEHSLPA LIQIRHDWDQ YLVPSDHPKG NFVPQGWVLP PLPSNDIWAT AVKLH|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signalling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Will, C.L., et al. RNA 10(6):929-941(2004)
Park, E.J., et al. Nucleic Acids Res. 27(6):1524-1530(1999)
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