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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   PDCD7 Antibody (C-term)   

PDCD7 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PDCD7 Antibody (C-term) AP13578b
    PDCD7 Antibody (C-term) (Cat. #AP13578b) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the PDCD7 antibody detected the PDCD7 protein (arrow).
  • WB - PDCD7 Antibody (C-term) AP13578b
    PDCD7 Antibody (C-term) (Cat. #AP13578b) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the PDCD7 antibody detected the PDCD7 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8N8D1
Other Accession Q9WTY1, NP_005698.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 390-419 aa
Additional Information
Other Names Programmed cell death protein 7, ES18, hES18, PDCD7
Target/Specificity This PDCD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-419 amino acids from the C-terminal region of human PDCD7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPDCD7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDCD7
Function Promotes apoptosis when overexpressed.
Cellular Location Nucleus. EMBL; AK096970; BAC04915.1; -; mRNA EMBL; AF083930; AAD20241.1; -; mRNA EMBL; BC016992; AAH16992.2; -; mRNA EMBL; BT007395; AAP36059.1; -; mRNA CCDS; CCDS10201.1; - RefSeq; NP_005698.1; NM_005707.1 UniGene; Hs.458596; - ProteinModelPortal; Q8N8D1; - SMR; Q8N8D1; - BioGrid; 115390; 27 IntAct; Q8N8D1; 9 MINT; MINT-1180347; - STRING; 9606.ENSP00000204549; - iPTMnet; Q8N8D1; - PhosphoSitePlus; Q8N8D1; - BioMuta; PDCD7; - DMDM; 38258174; - EPD; Q8N8D1; - MaxQB; Q8N8D1; - PaxDb; Q8N8D1; - PeptideAtlas; Q8N8D1; - PRIDE; Q8N8D1; - DNASU; 10081; - Ensembl; ENST00000204549; ENSP00000204549; ENSG00000090470 GeneID; 10081; - KEGG; hsa:10081; - UCSC; uc002aol.3; human CTD; 10081; - DisGeNET; 10081; - GeneCards; PDCD7; - HGNC; HGNC:8767; PDCD7 HPA; HPA049388; - MIM; 608138; gene neXtProt; NX_Q8N8D1; - OpenTargets; ENSG00000090470; - PharmGKB; PA33117; - eggNOG; ENOG410IVC0; Eukaryota eggNOG; ENOG41124DX; LUCA GeneTree; ENSGT00390000017392; - HOGENOM; HOG000115476; - HOVERGEN; HBG053537; - InParanoid; Q8N8D1; - OMA; PVPQRTH; - OrthoDB; EOG091G0R7S; - PhylomeDB; Q8N8D1; - TreeFam; TF332996; - BioCyc; ZFISH:ENSG00000090470-MONOMER; - Reactome; R-HSA-72165; mRNA Splicing - Minor Pathway ChiTaRS; PDCD7; human GeneWiki; PDCD7; - GenomeRNAi; 10081; - PRO; PR:Q8N8D1; - Proteomes; UP000005640; Chromosome 15 Bgee; ENSG00000090470; - CleanEx; HS_PDCD7; - ExpressionAtlas; Q8N8D1; baseline and differential Genevisible; Q8N8D1; HS GO; GO:0005654; C:nucleoplasm; TAS:Reactome GO; GO:0005689; C:U12-type spliceosomal complex; IDA:HGNC GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome GO; GO:0051384; P:response to glucocorticoid; ISS:HGNC GO; GO:0008380; P:RNA splicing; IC:HGNC InterPro; IPR031974; PDCD7 Pfam; PF16021; PDCD7; 1 1: Evidence at protein level; Apoptosis; Coiled coil; Complete proteome; Nucleus; Reference proteome; Repeat CHAIN 1 485 Programmed cell death protein 7 /FTId=PRO_0000058269 COILED 232 335 COILED 362 411 COMPBIAS 4 129 Pro-rich COMPBIAS 236 278 Arg/Glu-rich CONFLICT 292 292 Q -> GE (in Ref. 2; AAD20241) CONFLICT 303 303 S -> A (in Ref. 2; AAD20241) SEQUENCE 485 AA; 54700 MW; FF907D6D2187832A CRC64; MALPPFFGQG RPGPPPPQPP PPAPFGCPPP PLPSPAFPPP LPQRPGPFPG ASAPFLQPPL ALQPRASAEA SRGGGGAGAF YPVPPPPLPP PPPQCRPFPG TDAGERPRPP PPGPGPPWSP RWPEAPPPPA DVLGDAALQR LRDRQWLEAV FGTPRRAGCP VPQRTHAGPS LGEVRARLLR ALRLVRRLRG LSQALREAEA DGAAWVLLYS QTAPLRAELA ERLQPLTQAA YVGEARRRLE RVRRRRLRLR ERAREREAER EAEAARAVER EQEIDRWRVK CVQEVEEKKR EQELKAAADG VLSEVRKKQA DTKRMVDILR ALEKLRKLRK EAAARKGVCP PASADETFTH HLQRLRKLIK KRSELYEAEE RALRVMLEGE QEEERKRELE KKQRKEKEKI LLQKREIESK LFGDPDEFPL AHLLEPFRQY YLQAEHSLPA LIQIRHDWDQ YLVPSDHPKG NFVPQGWVLP PLPSNDIWAT AVKLH
Research Areas
Citations (0)

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Background

This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signalling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.

References

Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Will, C.L., et al. RNA 10(6):929-941(2004)
Park, E.J., et al. Nucleic Acids Res. 27(6):1524-1530(1999)

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$ 295.00
$ 99.00
Cat# AP13578b
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(40 western blots)
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