|Application ||WB, IHC-P, E|
|Calculated MW||45143 Da|
|Antigen Region||344-372 aa|
|Other Names||Testis-specific Y-encoded-like protein 5, TSPY-like protein 5, TSPYL5, KIAA1750|
|Target/Specificity||This TSPYL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-372 amino acids from the C-terminal region of human TSPYL5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TSPYL5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Kim, E.J., et al. Biochem. Biophys. Res. Commun. 392(3):448-453(2010)
Jung, Y., et al. Lab. Invest. 88(2):153-160(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
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