|Application ||WB, IHC-P, E|
|Other Accession||O35372, Q5BIN6, NP_005767.1|
|Calculated MW||16699 Da|
|Antigen Region||76-104 aa|
|Other Names||Protein cornichon homolog 1, CNIH-1, Cornichon family AMPA receptor auxiliary protein 1, Protein cornichon homolog, T-cell growth-associated molecule 77, TGAM77, CNIH1, CNIH, CNIL|
|Target/Specificity||This CNIH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-104 amino acids from the C-terminal region of human CNIH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CNIH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the selective transport and maturation of TGF-alpha family proteins.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane. Note=Located primarily in the ER; may cycle between the ER and the Golgi apparatus|
|Tissue Location||Highly expressed in heart, liver, skeletal muscle, pancreas, adrenal medulla and cortex, thyroid, testis, spleen, appendix, peripheral blood lymphocytes and bone marrow Lower expression found in brain, placenta, lung, kidney, ovary, small intestine, stomach, lymph node, thymus and fetal liver Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study)|
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Provided below are standard protocols that you may find useful for product applications.
CNIH is involved in the selective transport and maturation of TGF-alpha family proteins.
Castro, C.P., et al. J. Cell. Sci. 120 (PT 14), 2454-2466 (2007) :
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Utku, N., et al. Biochim. Biophys. Acta 1449(3):203-210(1999)
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