|Application ||WB, IHC-P, E|
|Calculated MW||101019 Da|
|Antigen Region||892-921 aa|
|Other Names||Autophagy-related protein 9B, APG9-like 2, Nitric oxide synthase 3-overlapping antisense gene protein, Protein sONE, ATG9B, APG9L2, NOS3AS|
|Target/Specificity||This ATG9B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 892-921 amino acids from the C-terminal region of human ATG9B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ATG9B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle (By similarity).|
|Cellular Location||Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Note=Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation- induced redistribution depends on ULK1 and ATG13|
|Tissue Location||Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial|
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Provided below are standard protocols that you may find useful for product applications.
ATG9B plays a role in autophagy (By similarity).
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Han, S., et al. Hum. Immunol. 71(7):727-730(2010) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010) Webber, J.L., et al. FEBS Lett. 584(7):1319-1326(2010) Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
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