|Application ||WB, E|
|Other Accession||Q6TEK3, Q6TEK5, NP_775788.2|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||19836 Da|
|Antigen Region||19-47 aa|
|Other Names||Vitamin K epoxide reductase complex subunit 1-like protein 1, VKORC1-like protein 1, VKORC1L1|
|Target/Specificity||This VKORC1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human VKORC1L1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VKORC1L1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins.|
|Cellular Location||Endoplasmic reticulum membrane; Multi- pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Yin, T., et al. Thromb. Res. 122(2):179-184(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Rost, S., et al. Nature 427(6974):537-541(2004)
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