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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TLR7 Antibody (C-term)   

TLR7 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TLR7 Antibody (C-term) AP13712B
    TLR7 Antibody (C-term) (Cat. #AP13712b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TLR7 antibody detected the TLR7 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NYK1
Other Accession P58681, NP_057646.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 120922 Da
Antigen Region 899-926 aa
Additional Information
Gene ID 51284
Other Names Toll-like receptor 7, TLR7
Target/Specificity This TLR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 899-926 amino acids from the C-terminal region of human TLR7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTLR7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TLR7
Function Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist
Tissue Location Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Manuse, M.J., et al. Virology 405(2):383-389(2010)
Cros, J., et al. Immunity 33(3):375-386(2010)
Shen, N., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15838-15843(2010)
Enevold, C., et al. Mult. Scler. 16(8):942-949(2010)

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$ 295.00
$ 99.00
Cat# AP13712B
(40 western blots)
Availability: In Stock
Bulk Size
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