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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CD27 Antibody (C-term)   

CD27 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CD27 Antibody (C-term) AP13740b
    CD27 Antibody (C-term) (Cat. #AP13740b) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the CD27 antibody detected the CD27 protein (arrow).
  • WB - CD27 Antibody (C-term) AP13740b
    Western blot analysis of CD27 (arrow) using rabbit polyclonal CD27 Antibody (C-term) (Cat. #AP13740b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD27 gene.
  • FC - CD27 Antibody (C-term) AP13740b
    CD27 Antibody (C-term) (Cat. #AP13740b) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P26842
Other Accession NP_001233.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 29137 Da
Antigen Region 196-225 aa
Additional Information
Gene ID 939
Other Names CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7
Target/Specificity This CD27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-225 amino acids from the C-terminal region of human CD27.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD27 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD27
Synonyms TNFRSF7
Function Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Found in most T-lymphocytes.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.


Jiang, J., et al. J. Clin. Immunol. 30(4):566-573(2010)
Arimoto-Miyamoto, K., et al. Immunology 130(1):137-149(2010)
Mizuochi, T., et al. J. Interferon Cytokine Res. 30(4):243-252(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Neron, S., et al. Arch. Immunol. Ther. Exp. (Warsz.) 57(6):447-458(2009)

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$ 295.00
$ 99.00
Cat# AP13740b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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