- Antibodies
- New
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Tag
- Peptides
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Amino Acids
- Tag
- Biological Process >
- Proteins
- RNAi
- FL cDNA Clones
- Cell/Tissues/Lysates
ARHGDIB Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
Australia Austria Belgium Brazil Bulgaria Canada China Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland India Indonesia Ireland Israel Italy Japan Korea Latvia Lithuania Luxembourg Macedonia Malaysia Malta Netherlands Norway Pakistan Poland Portugal Romania Serbia Singapore Slovakia Slovenia Spain Sweden Switzerland Taiwan Turkey United Kingdom United States Vietnam Others 
|
|||
|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP13743b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP13743b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ARHGDIB Antibody (C-term) - Product info | |
| Application | WB, IHC
|
| Primary Accession | P52566 |
| Other Accession | NP_001166.3 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 22988 Da |
ARHGDIB Antibody (C-term) - Additional info | |
| Gene ID 397 | |
| Other Names ARHGDIB; GDIA2; GDID4; RAP1GN1; Rho GDP-dissociation inhibitor 2; Ly-GDI; Rho-GDI beta | |
| Target/Specificity This ARHGDIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-188 amino acids from the C-terminal region of human ARHGDIB. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ARHGDIB Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ARHGDIB Antibody (C-term) - Protein Information | |
| Name ARHGDIB | |
| Synonyms GDIA2, GDID4, RAP1GN1 | |
| Function Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them | |
| Cellular Location Cytoplasm. | |
ARHGDIB Antibody (C-term) - Related products
AP13743b: ARHGDIB Antibody (C-term)
ARHGDIB Antibody (C-term) - Application data
-
ARHGDIB Antibody (C-term) (Cat. #AP13743b) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ARHGDIB antibody detected the ARHGDIB protein (arrow).
-
ARHGDIB Antibody (C-term) (Cat. #AP13743b)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ARHGDIB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
ARHGDIB Antibody (C-term) - Research Areas
Abgent welcomes feedback from its customers.
If you have used an Abgent product and would like to share how it has performed, please click on the
"Submit Review" button and provide the requested information. Our staff will examine and post your
review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Thank you for your support.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).
REFERENCES
Niu, H., et al. Oncol. Rep. 24(2):465-471(2010) Zhen, H., et al. Int. J. Gynecol. Cancer 20(3):316-322(2010) Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010) Said, N., et al. Cancer Metastasis Rev. 28 (3-4), 327-333 (2009) : Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)
