- CITATIONS: 1
|Application ||WB, E|
|Other Accession||P63329, P63328, P48452, NP_001124163.1, NP_000935.1|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||58688 Da|
|Antigen Region||438-466 aa|
|Other Names||Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit alpha isoform, PPP3CA, CALNA, CNA|
|Target/Specificity||This PPP3CA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-466 amino acids from the C-terminal region of human PPP3CA.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PPP3CA Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.|
|Cellular Location||Cell membrane. Cell membrane, sarcolemma. Nucleus. Note=Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle|
Provided below are standard protocols that you may find useful for product applications.
Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.
He, Z.H., et al. Eur. J. Appl. Physiol. 110(4):761-767(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Chiocco, M.J., et al. Subst Use Misuse 45(11):1809-1826(2010)
Yang, D., et al. Int. J. Mol. Med. 26(1):159-164(2010)
Bollo, M., et al. PLoS ONE 5 (8), E11925 (2010) :
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