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CELA3B Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CELA3B Antibody (N-term) AP13770a
    CELA3B Antibody (N-term) (Cat. #AP13770a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CELA3B antibody detected the CELA3B protein (arrow).
  • IHC-P - CELA3B Antibody (N-term) AP13770a
    CELA3B Antibody (N-term) (Cat. #AP13770a)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CELA3B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08861
Other Accession NP_031378.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 29263 Da
Antigen Region 70-98 aa
Additional Information
Gene ID 23436
Other Names Chymotrypsin-like elastase family member 3B, Elastase IIIB, Elastase-3B, Protease E, CELA3B, ELA3B
Target/Specificity This CELA3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human CELA3B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCELA3B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ELA3B
Function Efficient protease with alanine specificity but only little elastolytic activity.
Tissue Location Pancreas. Not detectable in keratinocytes.
Research Areas
Citations (0)

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Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.


Gao, J., et al. Oncol. Rep. 23(6):1683-1692(2010)
Teichmann, J., et al. Eur. J. Med. Res. 13(12):563-567(2008)
Hahn, J.U., et al. Pancreas 36(3):274-278(2008)
Mann, S.T., et al. Eur. J. Med. Res. 13(2):68-72(2008)
Vesterhus, M., et al. Diabetes Care 31(2):306-310(2008)

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$ 295.00
$ 99.00
Cat# AP13770a
(40 western blots)
Availability: In Stock
Bulk Size
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