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NNMT Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP13775c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP13775c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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NNMT Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | P40261 |
| Other Accession | NP_006160.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 29574 Da |
NNMT Antibody (Center) - Additional info | |
| Gene ID 4837 | |
| Other Names NNMT; Nicotinamide N-methyltransferase | |
| Target/Specificity This NNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-130 amino acids from the Central region of human NNMT. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions NNMT Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
NNMT Antibody (Center) - Protein Information | |
| Name NNMT | |
| Function Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds | |
| Cellular Location Cytoplasm. | |
| Tissue Location Predominantly expressed in the liver. A lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. Not detected in the brain or pancreas | |
NNMT Antibody (Center) - Related products
AP1024c: NNMT Antibody (Center)
AP13775c: NNMT Antibody (Center)
DC00096: Human NNMT cDNA Clone
NNMT Antibody (Center) - Application data
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NNMT Antibody (Center) (Cat. #AP13775c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the NNMT antibody detected the NNMT protein (arrow).
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NNMT Antibody (Center) (Cat. #AP13775c)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NNMT Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
NNMT Antibody (Center) - Research Areas
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BACKGROUND
N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor. [provided by RefSeq].
REFERENCES
Giusti, B., et al. Thromb. Haemost. 104(2):231-242(2010) Zhang, J., et al. J Zhejiang Univ Sci B 11(2):136-143(2010) Emanuelli, M., et al. Histol. Histopathol. 25(1):15-20(2010) Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) : van Driel, L.M., et al. J. Nutr. 139(12):2315-2321(2009)
