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GDI2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GDI2 Antibody (Center) AP13787c
    GDI2 Antibody (Center) (Cat. #AP13787c) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the GDI2 antibody detected the GDI2 protein (arrow).
  • IHC-P - GDI2 Antibody (Center) AP13787c
    GDI2 Antibody (Center) (AP13787c)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDI2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50395
Other Accession NP_001485.2, NP_001108628.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 50663 Da
Antigen Region 135-164 aa
Additional Information
Gene ID 2665
Other Names Rab GDP dissociation inhibitor beta, Rab GDI beta, Guanosine diphosphate dissociation inhibitor 2, GDI-2, GDI2, RABGDIB
Target/Specificity This GDI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the Central region of human GDI2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGDI2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GDI2
Synonyms RABGDIB
Function Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Cellular Location Cytoplasm. Membrane; Peripheral membrane protein
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms.


Rikova, K., et al. Cell 131(6):1190-1203(2007)
Sun, Z.L., et al. Biochim. Biophys. Acta 1774(6):764-771(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Shin, B.K., et al. J. Biol. Chem. 278(9):7607-7616(2003)

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$ 295.00
$ 99.00
Cat# AP13787c
(40 western blots)
Availability: In Stock
Bulk Size
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