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DCBLD2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - DCBLD2 Antibody (C-term) AP13827b
    DCBLD2 Antibody (C-term) (Cat. #AP13827b) western blot analysis in mouse NIH-3T3,Neuro-2a cell line and mouse stomach tissue and U251,A2058,A375,Sk-Br-3,T47D cell line lysates (35ug/lane).This demonstrates the DCBLD2 antibody detected the DCBLD2 protein (arrow).
    detail
  • FC - DCBLD2 Antibody (C-term) AP13827b
    DCBLD2 Antibody (C-term) (Cat. #AP13827b) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, WB, E
Primary Accession Q96PD2
Other Accession NP_563615.3
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 85035 Da
Antigen Region 538-567 aa
Additional Information
Gene ID 131566
Other Names Discoidin, CUB and LCCL domain-containing protein 2, CUB, LCCL and coagulation factor V/VIII-homology domains protein 1, Endothelial and smooth muscle cell-derived neuropilin-like protein, DCBLD2, CLCP1, ESDN
Target/Specificity This DCBLD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 538-567 amino acids from the C-terminal region of human DCBLD2.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDCBLD2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCBLD2
Synonyms CLCP1, ESDN
Cellular Location Membrane; Single- pass type I membrane protein
Tissue Location Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells
Research Areas
Citations (0)
citation

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Background

DCBLD2, otherwise known as ESDN (endothelial and smooth muscle cell-derived neuropilin-like molecule) is a novel type-I transmembrane protein with the longest cleavable secretory signal sequence among eukaryotes. It is expressed in various tissues; particularly highly expressed in cultured vascular smooth muscle cells. DCBLD2 is considered to play a role in regulation of vascular cell growth and may have a wide variety of functions in other tissues including the nervous system, like neuropilins.

References

Rose, J. Phd, et al. Mol. Med. (2010) In press :
Guo, X., et al. J. Biol. Chem. 284(43):29376-29382(2009)
Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)
Kim, M., et al. Mol. Cancer Res. 6(2):222-230(2008)
Sadeghi, M.M., et al. Am. J. Transplant. 7(9):2098-2105(2007)

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$ 182.50
$ 70.00
Cat# AP13827b
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