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Mouse Myo3b Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Myo3b Antibody (N-term) AP13924a
    Mouse Myo3b Antibody (N-term) (Cat. #AP13924a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the Myo3b antibody detected the Myo3b protein (arrow).
    detail
  • WB - Mouse Myo3b Antibody (N-term) AP13924a
    Mouse Myo3b Antibody (N-term) (Cat. #AP13924a) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Myo3b antibody detected the Myo3b protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q1EG27
Other Accession NP_796350.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 148099 Da
Antigen Region 300-329 aa
Additional Information
Gene ID 329421
Other Names Myosin-IIIb, Myo3b
Target/Specificity This Mouse Myo3b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-329 amino acids from the N-terminal region of mouse Myo3b.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Myo3b Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Myo3b
Function Probable actin-based motor with a protein kinase activity (By similarity). Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern (PubMed:26754646). Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments (PubMed:22264607).
Cellular Location Cytoplasm, cytoskeleton. Cell projection, stereocilium
Tissue Location Expressed in the cochlear hair cells (at protein level) (PubMed:26754646). Expressed in utricle hair bundles (at protein level) (PubMed:26926603).
Research Areas
Citations (0)
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Background

Probable actin-based motor with a protein kinase activity (By similarity).

References

Katti, C., et al. Exp. Eye Res. 89(2):224-237(2009)

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$ 365.00
$ 140.00
Cat# AP13924a
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