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VTI1B Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - VTI1B Antibody (Center) AP13952c
    VTI1B Antibody (Center) (Cat. #AP13952c) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the VTI1B antibody detected the VTI1B protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9UEU0
Other Accession O88384, NP_006361.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 26688 Da
Antigen Region 59-86 aa
Additional Information
Gene ID 10490
Other Names Vesicle transport through interaction with t-SNAREs homolog 1B, Vesicle transport v-SNARE protein Vti1-like 1, Vti1-rp1, VTI1B, VTI1, VTI1L, VTI1L1, VTI2
Target/Specificity This VTI1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the Central region of human VTI1B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsVTI1B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VTI1B
Synonyms VTI1, VTI1L, VTI1L1, VTI2
Function V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
Cellular Location Early endosome membrane; Single-pass type IV membrane protein. Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane. Cytoplasmic granule. Recycling endosome membrane; Single-pass type IV membrane protein
Tissue Location Expressed in all tissues examined.
Research Areas
Citations (0)
citation

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Background

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.

References

Furuta, N., et al. Mol. Biol. Cell 21(6):1001-1010(2010)
Bilan, F., et al. Exp. Cell Res. 314 (11-12), 2199-2211 (2008) :
Hirst, J., et al. Mol. Biol. Cell 15(12):5593-5602(2004)
Yan, Q., et al. J. Biol. Chem. 279(18):18270-18276(2004)
Martinez-Arca, S., et al. Proc. Natl. Acad. Sci. U.S.A. 100(15):9011-9016(2003)

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$ 182.50
$ 70.00
Cat# AP13952c
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