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GDPD3 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GDPD3 Antibody (N-term) AP13964A
    Anti-GDPD3 Antibody (N-term) at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 36 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
  • WB - GDPD3 Antibody (N-term) AP13964A
    GDPD3 Antibody (N-term) (Cat. #AP13964a) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the GDPD3 antibody detected the GDPD3 protein (arrow).
    detail
  • IHC-P - GDPD3 Antibody (N-term) AP13964A
    GDPD3 Antibody (N-term) (Cat. #AP13964a)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDPD3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q7L5L3
Other Accession NP_077283.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 36596 Da
Antigen Region 17-46 aa
Additional Information
Gene ID 79153
Other Names Glycerophosphodiester phosphodiesterase domain-containing protein 3, 31--, GDPD3
Target/Specificity This GDPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human GDPD3.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGDPD3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GDPD3 (HGNC:28638)
Function Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines (PubMed:27637550). Shows a preference for 1-O-alkyl-sn-glycero-3- phosphocholine (lyso-PAF), lysophosphatidylcholine (lyso-PC) and N- acylethanolamine lysophospholipids (PubMed:27637550). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine.
Cellular Location Membrane {ECO:0000250|UniProtKB:Q99LY2}; Multi- pass membrane protein {ECO:0000250|UniProtKB:Q99LY2}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q99LY2}. Endoplasmic reticulum. Note=Partially co-localized with CANX. {ECO:0000250|UniProtKB:Q99LY2}
Tissue Location Widely expressed, with high level in kidney and ovary.
Research Areas
Citations (0)
citation

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Background

The exact function of this protein remains unknown.

References

Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :

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$ 365.00
$ 140.00
Cat# AP13964A
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