GDPD3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
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Primary Accession | Q7L5L3 |
Other Accession | NP_077283.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 36596 Da |
Antigen Region | 17-46 aa |
Gene ID | 79153 |
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Other Names | Glycerophosphodiester phosphodiesterase domain-containing protein 3, 31--, GDPD3 |
Target/Specificity | This GDPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human GDPD3. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GDPD3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GDPD3 (HGNC:28638) |
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Function | Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines (PubMed:27637550). Shows a preference for 1-O-alkyl-sn-glycero-3- phosphocholine (lyso-PAF), lysophosphatidylcholine (lyso-PC) and N- acylethanolamine lysophospholipids (PubMed:27637550). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine. |
Cellular Location | Membrane {ECO:0000250|UniProtKB:Q99LY2}; Multi- pass membrane protein {ECO:0000250|UniProtKB:Q99LY2}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q99LY2}. Endoplasmic reticulum. Note=Partially co-localized with CANX. {ECO:0000250|UniProtKB:Q99LY2} |
Tissue Location | Widely expressed, with high level in kidney and ovary. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The exact function of this protein remains unknown.
References
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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