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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   CHRNA5 Antibody (Center)   

CHRNA5 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CHRNA5 Antibody (Center) AP14006c
    CHRNA5 Antibody (Center) (Cat. #AP14006c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CHRNA5 antibody detected the CHRNA5 protein (arrow).
  • WB - CHRNA5 Antibody (Center) AP14006c
    CHRNA5 Antibody (Center) (Cat. #AP14006c) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the CHRNA5 antibody detected the CHRNA5 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P30532
Other Accession Q8SPU7, NP_000736.2
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53054 Da
Antigen Region 187-216 aa
Additional Information
Gene ID 1138
Other Names Neuronal acetylcholine receptor subunit alpha-5, CHRNA5, NACHRA5
Target/Specificity This CHRNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human CHRNA5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCHRNA5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms NACHRA5
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Cellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).


Wessel, J., et al. Neuropsychopharmacology 35(12):2392-2402(2010)
Erlich, P.M., et al. Hum. Genet. 128(5):491-499(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Falvella, F.S., et al. J. Natl. Cancer Inst. 102(17):1366-1370(2010)
Li, M.D., et al. PLoS ONE 5 (8), E12183 (2010) :

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$ 295.00
$ 99.00
Cat# AP14006c
(40 western blots)
Availability: In Stock
Bulk Size
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