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>   home   >   Products   >   Primary Antibodies   >   HNRNPM Antibody (N-term)   

HNRNPM Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HNRNPM Antibody (N-term) AP14009a
    HNRNPM Antibody (N-term) (Cat. #AP14009a) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the HNRNPM antibody detected the HNRNPM protein (arrow).
  • IHC-P - HNRNPM Antibody (N-term) AP14009a
    HNRNPM Antibody (N-term) (AP14009a)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HNRNPM Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P52272
Other Accession NP_112480.2, NP_005959.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 77516 Da
Antigen Region 21-50 aa
Additional Information
Gene ID 4670
Other Names Heterogeneous nuclear ribonucleoprotein M, hnRNP M, HNRNPM, HNRPM, NAGR1
Target/Specificity This HNRNPM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human HNRNPM.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHNRNPM Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HNRPM, NAGR1
Function Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
Cellular Location Nucleus, nucleolus {ECO:0000269|Ref.5}.
Citations (0)

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This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated.


Lleres, D., et al. EMBO Rep. 11(6):445-451(2010)
Marko, M., et al. Exp. Cell Res. 316(3):390-400(2010)
Russo, A., et al. Biochim. Biophys. Acta 1779(12):820-829(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Huang, X., et al. Sci. China, C, Life Sci. 43(6):648-654(2000)

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$ 295.00
$ 99.00
Cat# AP14009a
(40 western blots)
Availability: In Stock
Bulk Size
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