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BAG2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - BAG2 Antibody (C-term) AP14053b
    BAG2 Antibody (C-term) (Cat. #AP14053b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the BAG2 antibody detected the BAG2 protein (arrow).
  • IHC-P - BAG2 Antibody (C-term) AP14053b
    BAG2 Antibody (C-term) (AP14053b)immunohistochemistry analysis in formalin fixed and paraffin embedded human ovarian carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BAG2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95816
Other Accession Q91YN9, Q3ZBG5, NP_004273.1
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23772 Da
Antigen Region 148-176 aa
Additional Information
Gene ID 9532
Other Names BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2, BAG2
Target/Specificity This BAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human BAG2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBAG2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BAG2
Function Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.
Research Areas
Citations ( 0 )


BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq].


Arndt, V., et al. Mol. Biol. Cell 16(12):5891-5900(2005)
Dai, Q., et al. J. Biol. Chem. 280(46):38673-38681(2005)
Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004)
Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)

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$ 295.00
$ 99.00
Cat# AP14053b
(40 western blots)
Availability: In Stock
Bulk Size
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