- Antibodies
- New
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Tag
- Peptides
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Amino Acids
- Tag
- Biological Process >
- Proteins
- RNAi
- FL cDNA Clones
- Cell/Tissues/Lysates
BAG2 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
Australia Austria Belgium Brazil Bulgaria Canada China Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland India Indonesia Ireland Israel Italy Japan Korea Latvia Lithuania Luxembourg Macedonia Malaysia Malta Netherlands Norway Pakistan Poland Portugal Romania Serbia Singapore Slovakia Slovenia Spain Sweden Switzerland Taiwan Turkey United Kingdom United States Vietnam Others 
|
|||
|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP14053b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP14053b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
BAG2 Antibody (C-term) - Product info | |
| Application | WB, IHC
|
| Primary Accession | O95816 |
| Other Accession | Q91YN9, Q3ZBG5, NP_004273.1 |
| Reactivity | Human |
| Predicted | Bovine, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 23772 Da |
BAG2 Antibody (C-term) - Additional info | |
| Gene ID 9532 | |
| Other Names BAG2; BAG family molecular chaperone regulator 2; Bcl-2-associated athanogene 2 | |
| Target/Specificity This BAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the C-terminal region of human BAG2. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions BAG2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
BAG2 Antibody (C-term) - Protein Information | |
| Name BAG2 | |
| Function Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release | |
BAG2 Antibody (C-term) - Related products
AP14053b: BAG2 Antibody (C-term)
BAG2 Antibody (C-term) - Application data
-
BAG2 Antibody (C-term) (Cat. #AP14053b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the BAG2 antibody detected the BAG2 protein (arrow).
-
BAG2 Antibody (C-term) (AP14053b)immunohistochemistry analysis in formalin fixed and paraffin embedded human ovarian carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BAG2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
BAG2 Antibody (C-term) - Research Areas
Abgent welcomes feedback from its customers.
If you have used an Abgent product and would like to share how it has performed, please click on the
"Submit Review" button and provide the requested information. Our staff will examine and post your
review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Thank you for your support.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq].
REFERENCES
Arndt, V., et al. Mol. Biol. Cell 16(12):5891-5900(2005) Dai, Q., et al. J. Biol. Chem. 280(46):38673-38681(2005) Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004) Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004) Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
