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SEC22B Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP14062c 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP14062c-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
  • Specification
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  • Backgrounds

SEC22B Antibody (Center) - Product info

ApplicationWB, IHC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionO75396
Other AccessionQ4KM74, O08547, O08595, NP_004883.2
ReactivityHuman
PredictedHamster, Mouse, Rat
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW24593 Da

SEC22B Antibody (Center) - Additional info

Gene ID 9554
Other Names
SEC22B; SEC22L1; Vesicle-trafficking protein SEC22b; ER-Golgi SNARE of 24 kDa; SEC22 vesicle-trafficking protein homolog B; SEC22 vesicle-trafficking protein-like 1
Target/Specificity
This SEC22B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-104 amino acids from the Central region of human SEC22B.
Dilution
WB~~1:100~500
IHC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
SEC22B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.

SEC22B Antibody (Center) - Protein Information

Name SEC22B
Synonyms SEC22L1
Function
SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER
Cellular Location
Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type IV membrane protein (By similarity). Golgi apparatus membrane; Single-pass type IV membrane protein (By similarity). Endoplasmic reticulum membrane; Single-pass type IV membrane protein (By similarity). Melanosome Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV

SEC22B Antibody (Center) - Related products

AP14062c: SEC22B Antibody (Center)

RI14743: SEC22B predesign siRNA

DC00634: Human SEC22B cDNA Clone

LY13932a: SEC22B Over-expression Lysate

AT3805a: SEC22L1 Antibody (monoclonal) (M01)

SEC22B Antibody (Center) - Application data

  • SEC22B Antibody (Center) (Cat. #AP14062c) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SEC22B antibody detected the SEC22B protein (arrow).

  • SEC22B Antibody (Center) (AP14062c)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SEC22B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

SEC22B Antibody (Center) - Research Areas

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BACKGROUND

The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins.

REFERENCES

Matsuoka, S., et al. Science 316(5828):1160-1166(2007) Chi, A., et al. J. Proteome Res. 5(11):3135-3144(2006) Okumura, A.J., et al. J. Biol. Chem. 281(7):4495-4506(2006) Breuza, L., et al. J. Biol. Chem. 279(45):47242-47253(2004) Nakajima, K., et al. EMBO J. 23(16):3216-3226(2004)