|Application ||WB, E|
|Calculated MW||42529 Da|
|Antigen Region||46-75 aa|
|Other Names||Carboxypeptidase O, CPO, 3417-, CPO|
|Target/Specificity||This CPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the N-terminal region of human CPO.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CPO Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Carboxypeptidase which preferentially cleaves C-terminal acidic residues from peptides and proteins. Can also cleave C- terminal hydrophobic amino acids, with a preference for small residues over large residues.|
|Cellular Location||Apical cell membrane; Lipid-anchor, GPI-anchor|
|Tissue Location||Detected in enterocytes of the ileum.|
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Provided below are standard protocols that you may find useful for product applications.
Probable carboxypeptidase which may cleave proteins with C-terminal acidic residues (By similarity).
Hillier, L.W., et al. Nature 434(7034):724-731(2005) Wei, S., et al. J. Biol. Chem. 277(17):14954-14964(2002)
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