|Application ||WB, IF, FC, IHC-P, E|
|Other Accession||P01343, NP_000609.1|
|Antigen Region||115-144 aa|
|Other Names||IGF1; IBP1; Insulin-like growth factor I; Mechano growth factor; Somatomedin-C|
|Target/Specificity||This IGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 amino acids from the C-terminal region of human IGF1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IGF1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
Li, M., et al. J. Biol. Chem. 285(40):30480-30488(2010)
Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Szczesny, G., et al. Arch Orthop Trauma Surg (2010) In press :
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