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SOX9 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP1409c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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SOX9 Antibody (Center) - Product info | |
| Application | WB, FC
|
| Primary Accession | P48436 |
| Other Accession | O18896 |
| Reactivity | Human |
| Predicted | Pig |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 56137 Da |
SOX9 Antibody (Center) - Additional info | |
| Gene ID 6662 | |
| Other Names SOX9; Transcription factor SOX-9 | |
| Target/Specificity This SOX9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238~268 amino acids from the Center region of human SOX9. | |
| Dilution WB~~1:100~500WB~~1:1000 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Then the antibody is purified by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions SOX9 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
SOX9 Antibody (Center) - Protein Information | |
| Name SOX9 | |
| Function Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes | |
| Cellular Location Nucleus (Potential). | |
SOX9 Antibody (Center) - Related products
AP1409a: SOX9 Antibody (N-term)
AP1409c: SOX9 Antibody (Center)
BP1409a: SOX9 Antibody (N-term) Blocking Peptide
BP1409c: SOX9 Antibody (Center) Blocking Peptide
SOX9 Antibody (Center) - Application data
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Western blot analysis of anti-SOX9 Antibody (Center) (RB13405) in HepG2 cell line lysates (35ug/lane). SOX9(arrow) was detected using the purified Pab (1:60 dilution).
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Flow cytometric analysis of HepG2 cells using SOX9 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
SOX9 Antibody (Center) - Research Areas
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BACKGROUND
SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
REFERENCES
Malki,S., Cancer Lett. 255 (2), 182-193 (2007) Passeron,T., Proc. Natl. Acad. Sci. U.S.A. 104 (35), 13984-13989 (2007)
