|Application ||WB, E|
|Calculated MW||103080 Da|
|Antigen Region||652-680 aa|
|Other Names||Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, Serine/threonine-protein kinase NIK, Map3k14, Nik|
|Target/Specificity||This Mouse Map3k14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 652-680 amino acids from the C-terminal region of mouse Map3k14.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Map3k14 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non- canonical pathway. Could act in a receptor-selective manner.|
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Provided below are standard protocols that you may find useful for product applications.
Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
Bhattacharyya, S., et al. Exp. Cell Res. 316(19):3317-3327(2010)
Maeda, Y., et al. Int. Immunol. 22(6):515-525(2010)
Sanjo, H., et al. J. Biol. Chem. 285(22):17148-17155(2010)
Takeshima, T., et al. Cancer Res. 70(7):2697-2706(2010)
Moro, K., et al. Nature 463(7280):540-544(2010)
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