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HDC Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - HDC Antibody (N-term) AP14174a
    HDC Antibody (N-term) (Cat. #AP14174a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HDC antibody detected the HDC protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P19113
Other Accession NP_002103.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 74141 Da
Antigen Region 147-178 aa
Additional Information
Gene ID 3067
Other Names Histidine decarboxylase, HDC, HDC
Target/Specificity This HDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-178 amino acids from the N-terminal region of human HDC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHDC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HDC
Function Catalyzes the biosynthesis of histamine from histidine.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.

References

Gervasini, G., et al. Allergy (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Ercan-Sencicek, A.G., et al. N. Engl. J. Med. 362(20):1901-1908(2010)
Jeong, H.J., et al. Cell. Mol. Life Sci. 66(7):1309-1319(2009)
Siezen, C.L., et al. Pediatr. Infect. Dis. J. 28(4):333-335(2009)

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$ 365.00
$ 140.00
Cat# AP14174a
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