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RGS9 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RGS9 Antibody (N-term) AP14236a
    RGS9 Antibody (N-term) (Cat. #AP14236a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RGS9 antibody detected the RGS9 protein (arrow).
  • IHC-P - RGS9 Antibody (N-term) AP14236a
    RGS9 Antibody (N-term) (AP14236a)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RGS9 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75916
Other Accession NP_001075424.1, NP_003826.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 76966 Da
Antigen Region 149-178 aa
Additional Information
Gene ID 8787
Other Names Regulator of G-protein signaling 9, RGS9, RGS9
Target/Specificity This RGS9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the N-terminal region of human RGS9.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRGS9 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RGS9
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).
Cellular Location Isoform 3: Membrane; Peripheral membrane protein. Note=Isoform 3 is targeted to the membrane via its interaction with RGS9BP.
Tissue Location Highly expressed in the caudate and putamen, lower levels found in the hypothalamus and nucleus accumbens and very low levels in cerebellum. Not expressed in globus pallidus or cingulate cortex. Isoform 2 is expressed predominantly in pineal gland and retina. Isoform 3 is expressed in retina (abundant in photoreceptors)
Research Areas
Citations (0)

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This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene.


Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)
Celver, J., et al. J. Neurochem. 114(3):739-749(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Greenbaum, L., et al. Psychiatr. Genet. 20(1):47-48(2010)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

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$ 295.00
$ 99.00
Cat# AP14236a
(40 western blots)
Availability: In Stock
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