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TMC8 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TMC8 Antibody (N-term) AP14243A
    TMC8 Antibody (N-term) (Cat. #AP14243a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TMC8 antibody detected the TMC8 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IU68
Other Accession NP_689681.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 81641 Da
Antigen Region 50-79 aa
Additional Information
Gene ID 147138
Other Names Transmembrane channel-like protein 8, Epidermodysplasia verruciformis protein 2, TMC8, EVER2, EVIN2
Target/Specificity This TMC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human TMC8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTMC8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMC8
Synonyms EVER2, EVIN2
Function Probable ion channel.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Expressed in placenta, prostate and testis.
Research Areas
Citations (0)

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Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs.


McDermott, D.F., et al. Pediatr Dermatol 26(3):306-310(2009)
Patel, A.S., et al. Int. J. Cancer 122(10):2377-2379(2008)
Zavattaro, E., et al. J. Invest. Dermatol. 128(3):732-735(2008)
Lazarczyk, M., et al. J. Exp. Med. 205(1):35-42(2008)
Rady, P.L., et al. Br. J. Dermatol. 157(4):831-833(2007)

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$ 295.00
$ 99.00
Cat# AP14243A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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