|Application ||WB, FC, E|
|Calculated MW||44960 Da|
|Antigen Region||302-331 aa|
|Other Names||Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform, Phosphorylase kinase subunit gamma-1, Serine/threonine-protein kinase PHKG1, Phkg1, Phkg|
|Target/Specificity||This Mouse Phkg1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-331 amino acids from the C-terminal region of mouse Phkg1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Phkg1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
Suto, J., et al. J. Vet. Med. Sci. 66(9):1033-1038(2004)
Visel, A., et al. Nucleic Acids Res. 32 (DATABASE ISSUE), D552-D556 (2004) :
Takenaka, M., et al. Kidney Int. 53(3):562-572(1998)
Maichele, A.J., et al. Mamm. Genome 5(1):15-18(1994)
Bender, P.K., et al. Genet. Anal. Tech. Appl. 10 (3-4), 99-101 (1993) :
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