|Application ||WB, IHC-P, E|
|Calculated MW||36676 Da|
|Antigen Region||15-46 aa|
|Other Names||Retinal homeobox protein Rx, Retina and anterior neural fold homeobox protein, RAX, RX|
|Target/Specificity||This Rax antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-46 amino acids from the N-terminal region of human Rax.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Rax Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.|
|Tissue Location||Expressed in the developing eye and weakly expressed in the adult retina|
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Provided below are standard protocols that you may find useful for product applications.
Rax plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. It binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
Voronina,V.A., Hum. Mol. Genet. 13 (3), 315-322 (2004)
Mikkola,I., J. Biol. Chem. 276 (6), 4109-4118 (2001)
Mathers,P.H., Cell. Mol. Life Sci. 57 (2), 186-194 (2000)
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