|Application ||WB, IHC-P, E|
|Calculated MW||36676 Da|
|Antigen Region||15-46 aa|
|Other Names||Retinal homeobox protein Rx, Retina and anterior neural fold homeobox protein, RAX, RX|
|Target/Specificity||This Rax antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-46 amino acids from the N-terminal region of human Rax.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Rax Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.|
|Tissue Location||Expressed in the developing eye and weakly expressed in the adult retina|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Rax plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. It binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
Voronina,V.A., Hum. Mol. Genet. 13 (3), 315-322 (2004)
Mikkola,I., J. Biol. Chem. 276 (6), 4109-4118 (2001)
Mathers,P.H., Cell. Mol. Life Sci. 57 (2), 186-194 (2000)
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