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ING1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ING1 Antibody (N-term) AP14335a
    ING1 Antibody (N-term) (Cat. #AP14335a) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ING1 antibody detected the ING1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UK53
Other Accession NP_937862.1, NP_937861.1, NP_005528.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 46738 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 3621
Other Names Inhibitor of growth protein 1, ING1
Target/Specificity This ING1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ING1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsING1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ING1
Function Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene.
Cellular Location Nucleus.
Tissue Location Isoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines
Research Areas
Citations (0)

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This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.


Zhu, Z., et al. Hepatology 49(2):504-512(2009)
Sayan, B., et al. Hybridoma (Larchmt) (2009) In press :
Tallen, G., et al. Oncol. Res. 18 (2-3), 95-105 (2009) :
Halaschek-Wiener, J., et al. PLoS ONE 4 (8), E6641 (2009) :
Han, X., et al. Nat. Cell Biol. 10(11):1333-1340(2008)

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$ 295.00
$ 99.00
Cat# AP14335a
(40 western blots)
Availability: In Stock
Bulk Size
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