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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FRAT1 Antibody (C-term)   

FRAT1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FRAT1 Antibody (C-term) AP1436b
    Western blot analysis of lysates from SK-BR-3, K562 cell line (from left to right), using FRAT1 Antibody (C-term)(Cat. #AP1436b). AP1436b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
  • IHC-P - FRAT1 Antibody (C-term) AP1436b
    Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with FRAT1 antibody (C-term) (Cat.#AP1436b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92837
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 29093 Da
Antigen Region 244-274 aa
Additional Information
Gene ID 10023
Other Names Proto-oncogene FRAT1, Frequently rearranged in advanced T-cell lymphomas 1, FRAT-1, FRAT1
Target/Specificity This FRAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244-274 amino acids from the C-terminal region of human FRAT1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFRAT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FRAT1
Function Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
Cellular Location Cytoplasm.
Research Areas
Citations ( 0 )


FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis.


Hagen,T., J. Biol. Chem. 281 (46), 35021-35029 (2006)
Wang,Y., Br. J. Cancer 94 (5), 686-691 (2006)
Hino,S., J. Biol. Chem. 278 (16), 14066-14073 (2003)

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$ 295.00
$ 99.00
Cat# AP1436b
(40 western blots)
Availability: In Stock
Bulk Size
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